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What is Blastocyst Treatment?

Blastocyst transfer is an advanced IVF technique designed to increase the chances of a successful pregnancy. This process involves transferring a blastocyst, an embryo at the five-day stage of development, into the uterus. The blastocyst transfer in IVF mirrors the natural timing of when a naturally-conceived embryo enters the uterus, enhancing the likelihood of implantation and pregnancy. By selecting only the most viable embryos, this method ensures higher precision and success rates.
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Steps in the Blastocyst Transfer Process

  1. Ovarian Stimulation: Medications or injections are administered to the female to stimulate the release of eggs from the ovaries.
  2. Egg Release: An injection of Human Chorionic Gonadotrophin (hCG), known as the trigger, is given to aid in the final maturation and release of the eggs.
  3. Egg Retrieval: Performed 35-38 hours after the trigger, this procedure is conducted under ultrasound guidance while the patient is sedated.
  4. Semen Sample: Collected from the male partner, the semen is processed to select the healthiest sperm.
  5. Insemination: Depending on the technique, the selected sperm is either injected directly into the egg (ICSI) or placed with the egg for fertilization.
  6. Fertilization: The fertilized eggs are incubated and checked for fertilization after 16-18 hours.
  7. Embryo Formation: The embryos are cultured in the lab for 2 to 5 days.
  8. Blastocyst Stage: On the fifth day, the embryo reaches the blastocyst stage, ready for transfer.
  9. Embryo Transfer: The healthiest blastocyst is transferred into the uterus using a catheter. Typically, one or two blastocysts are transferred.
  10. Vitrification: Unused embryos are frozen and stored for future use, ensuring their health and viability.

Benefits of Blastocyst Transfer

  1. Improved Pregnancy Rates: Higher success rates compared to traditional embryo transfers.
  2. Reduced Risks of Multiple Births: Allows for the transfer of fewer embryos, lowering the risk of multiple pregnancies.
  3. Better Embryo Selection: Enables the selection of embryos with the highest chances of implantation and successful development.

Differences from Traditional IVF Procedures

  1. Timing: Traditional IVF transfers embryos on the 3rd or 4th day of development, whereas blastocyst transfer occurs on the 5th day.
  2. Natural Process: Blastocyst transfer aligns with the natural timing of embryo implantation, increasing the likelihood of success.

Success Rate

Studies show that the success rate of blastocyst transfer can be up to 60% higher than that of traditional embryo transfers.

Recommended Age and Fertility Levels

Blastocyst transfer is suitable for all IVF cases but is particularly recommended for females aged 35 and above, as it may offer better outcomes compared to regular embryo transfer.

Blastocyst Development Timeline

A blastocyst forms five to six days after fertilization, with cell layers dividing and separating to create a structure that supports and nourishes the developing fetus.
By optimizing the timing and selection of embryos, blastocyst transfer significantly enhances the success rates of IVF, offering hope to many aspiring parents.